What Is Metformin Hcl For Resource
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What is the difference between Metformin and Metformin HCL? My mother is taking Metformin and the doctor prescribed her with Metformin HCL and we were wondering the difference. We asked but can't remember...I think it is a waterpill added.

Pinky26 replied: "There is no difference between metformin and metformin hydrochloride. This product, trade named Glucophage and Glucophage XL, can be referred to by either name. The only thing can be the duration of the effect, one acts slower than the other."

Why cant you drink alcohol when taking Metformin HCL for diabetes? I know diabetics shouldnt drink because doing so lowers blood sugars. I am just wondering what the adverse effects would be regarding the use of alcohol while taking metformin. What, exactly,will happen?

lily replied: "You increase your risk of developing lactic acidosis if you take this drug and drink alcohol. This is fatal in up to 50% of cases, so it's very serious."

Morphious replied: "And more than the acidosis, you will have increased sugar lows, and the possibility of passing out all of a sudden. Both together would be fatal. Moreover, as I have experienced, you just don't feel good when you drink as you normally want to. You can have a "taste" - small amounts. When you have a regular drink, you will feel pretty bad for a while. I've been on it for three years now. Currently 1g twice a day. And, while I will have a really small glass of wine or beer - about 1 finger high - once in a while (meaning about 1 every other month), more than that will really upsets my insides."

Patrick O replied: "they both target the liver?"

Does METFORMIN HCL ER help with weight loss in women with PCOS? I can't find any good sites online with good info about it.

sokokl replied: "Yes, it could but I have the link to a site that may help you find more information (and they have messageboards on there too). The link is at:"

aesoprockfloats replied: "I began taking 500 mg of MET ER in January of last year...as the months went on I moved up to my final dose of 1500 mg. I lost 30 pounds by August. Starting the Met made me lose interest in greasy, fried, bad foods that I used to love. It makes you poop a lot. If you eat a diet free from lots of grease and carbs and excersies a little you should be able to lose weight. Also know that weight loss does not come until being on Met for at least 6 months."

Information on the pills IC Glimepiride 4mg and IC Metformin HCL 500 MG.I prefer info from ppl takin the pills Sorry for the short typing in the subject. I this question is for people who have taken/is taking/ knows someone who has taken the pills mentioned above. What was their sugar level before and after starting the pills and what where their side effects? My husbad just started the pills tonight. His sugar level is normally around 350 or so. Thanks.

Mr. Peachy replied: "Metformin is a pretty neat drug, but don't expect it and that other one to take the place of diet and exercise. Metformin helps his insulin work better to overcome the resistance of the cell walls allowing insulin to get the blood glucose into the cell more efficiently. It also helps slow the conversion of glycogen into glucose. Third, it slows the absorption of glucose in the intestine during digestion. [edit] Oh yeah, I forgot to tell you about Metformin side affects... occasional nausea or diarrhea (particularly in the beginning). Remote possibility of lactic acidosis... possibility increases with alcohol consumption. I'll get back to you in a minute. Okay, I thought so. Glimepiride is a sulfonylurea. That's a drug whose job is to force the pancreas to produce more insulin.... bad idea. Best idea is to naturally coax the body's cells to become less resistant to insulin. That way, his pancreas won't "wear out" forcing him to take insulin shots. Get that weight down, exercise, and improve the diet and avoid sulfonylureas if at all possible... yes, they're effective at lowering blood glucose, but how they do it is hardly the best way to get the job done. If you want to help him, I strongly urge both of you to learn as much about taking care of diabetes through healthy diet and daily exercise as you can. Begin here:"

Mrs. WC replied: "I agree with Mr Peachy. It's probably ok for your husband to take a combination pill or combination of pills until his sugar is under control. Then, you have to be really careful. I was taking Metaglip (Metformin/Glucotrol) and after I got my sugar down, it was crashing continuously. (My first readings were anywhere from 380 - 526). I quit taking the pills except when my sugar was over 180. Even at that, I'd wake up at 3 am looking for a fork, a cow and a bottle of chocolate syrup. (my way of saying I was feeling starved). I talked to my doctor, told him I'd rather take a shot when I needed it than to be cramming food in my face at 3 am. (or anytime of day really) He switched me to just the metformin. Like Mr. Peachy, I don't take my medication a lot of days, because my sugar is ok. But it's nice to have it if I need it."

far3oni711 replied: "Glimepiride... is an Oral Hypoglycemic Agent from the Sulfonylurea family..used for diabetics with type 2 diabetes. Mode of action.... Glimepiride distinctly lower the blood glucose level by both defects of NIDDM, by stimulating pancreatic beta cells to produce more insulin and induced increased activity of peripheral insulin intra cellular receptor. Metformin... is an Oral Hypoglycemic Agent from the Biguanide family..used for diabetics with type 2 diabetes ((specially obese ppl)). Mode of action... it works by.. 1) reducing hepatic gluconeogenesis, 2) decreases absorption of glucose from the gastrointestinal tract, 3) increases insulin sensitivity by increasing peripheral utilization of glucose. hope u a good life"

Can i take a aleve while taking metformin hcl? Anyone?

TONY C replied: "Yes. Take them with food."

Tin S replied: "Most pain relievers can cause stomach upset and possibly ulcers, however, the greater danger from Naproxen Sodium is that in recent studies it was linked to an increased risk of heart attack and stroke. These studies are ongoing. Still, do not use it or any other NSAID (non-steroidal anti-inflammatory drug) if you have high blood pressure, unless doctor approved. Naproxen sodium has been shown to impair the effectiveness of blood pressure medicines like ace inhibitors and beta blockers. I would just take plain old Aspirin. High doses of aspirin (300mg and over) prevent the production of prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause pain, swelling and inflammation. Hence a 300mg dose of aspirin is seen as a pain-relieving dose. Disprin dispersible tablets contain 300mg of aspirin and can be used to relieve pain and inflammation. Aspirin in low doses, eg 75-100mg, does not have this effect and is used instead as an anti-clotting or blood-thinning agent. Low doses of aspirin prevent the production of thromboxane by blood cells called platelets. Thromboxane is one of the chemicals that causes platelets to clump together and start off the clotting process. Stopping its production therefore reduces the likelihood of clots forming in the blood. Clots in the blood can cause a heart attack or stroke, and low dose aspirin is therefore used to prevent this in people who are at risk. See the factsheets linked at the end of this page for more information about this use of aspirin. Aspirin is also used in the emergency situation of a heart attack. Anyone who has the symptoms of a heart attack (chest pain, possibly radiating towards the arm or neck, shortness of breath) should take one 300mg aspirin tablet as soon as possible, as this has been shown to increase the chances of surviving a heart attack. This is because the aspirin prevents the blood clot that is blocking the supply of blood to the heart from growing any bigger. Many benefit to aspirin over other non-steroidal pain relievers."

Mr. Peachy replied: "While there are no known contraindications, after reading Tin's answer, I wouldn't. In fact, the one and only time I ever took that stuff, I had the worst case of heartburn in my entire 58 years."

I'm a diabetic and I was wondering if its safe to take Glipizide 5 mg & Metformin Hcl Tab 500 Mg together? I'm a new diabetic and my blood levels were really good and then they sort of spiked up and my doctor prescribed Glipizide 5 mg and Metformin Hcl Tab 500 Mg. I was just wondering if it is safe to take together? Just want to make sure my blood sugar dosen't drop too low.

john e russo md replied: "Although metformin and glipizide may be taken safely together glipizide and its relatives glyburide and glimiperide are archaic medications that have no place in the treatment of diabetics. If your physician would like I will happy to provide them with educational materials. Good luck - diabetes is not fun - but with medical options available today the outlook has never been better."

VERbal replied: "your doctor didn't prescribe you a high dose of those drugs. Glipizide's maximum dose is 20 mg and Metformin's 2500-3000 mg. The 2 drugs have different ways of action and both are beneficial in diabetes. The most recent recommendations suggest that diabetes treatment should begin with a combination therapy like in your case. Metformin does not cause blood glucose to drop too low. Gipizide can do this, but in special conditions ( high dose, if you take the drug and don't eat, high alcohol intake, high level of physical activity, impaired renal function, etc) I can see that you are afraid of hypoglycaemia, maybe you haven't experienced any yet, I cannot guarantee that it will never happen, but if you know the signs (and I think your doctor told you) you will recognise it and treat it (with a bit of sugar). Anyways, the dosage is low, and I think you should trust your doctor and follow the treatment."

BAR replied: "Some diabetic drugs work well together. They all work with different parts of your body. I would trust what your dr. prescribed."

Mad Roy replied: "These two drugs are very commonly prescribed together. They both help control blood sugar in diabetics. Your pharmacist should have printouts available on both drugs and be willing to give them to you. You may want to get and read a copy of How to Prevent and Treat Diabetes with Natural Medicine by Mike Murray. It is full of useful advice and information by an expert in the field. Good luck!"

try2bhelpful replied: "Yes, if your doctor prescribed it, it is safe. Be sure and eat something before you take it. Both are meant to help your Type II diabetes."

Robert b replied: "Dispite Dr.(?) Russo's statements, glipizide and metformin do have a legitimate place in diabetes therapy and please follow the instructions of you physician......if you need more information your pharmacist will be happy to give you detailed printed information on both drugs. They can be and are commonly prescribed together."

if a doctor prescribes you metformin hcl does that mean u necessarily have diabetes? ? a doctor prescribed me it a while back (when i took it, it tended to make me feel nauseous all the time. i ended up going to another doctor who took a blood test and he said i did not have diabetes... but he wanted me to keep taking the medicine but in a smaller dose. is there a reason for this?

Erica replied: "You could have insulin resistance which is not diabetes. That is what I have and I am on a low dose of metformin. All that metformin does is help you insulin work correctly. EDIT: Insulin resistance is a silent condition that increases the chances of developing diabetes and heart disease. Does not mean that you have diabetes at this point. (http://diabetes.niddk.nih.gov/DM/pubs/insulinresistance/)"

Gary B replied: "Yea, pretty much so. Diabetes canNOT be cured, but it can be controlled. if you do not continue on you diet, exercise, and medicine plan, the diabetes will return. Your first doctor found you to be diabetic. In addition to the medicine, he probably also told you about better dietary control, more exercise, and weight loss. So maybe you took him seriously..... Now, you go to a second doctor, but you have made some lifestyle changes, and you now have the diabetes under control. Controlled diabetes show the same test results as no diabetes. You STILL need the medicine, but the goal is to treat the diabetes with lifestyle changes, and reduce the medication, maybe even eliminate it as you lose weight and eat better. The doctor should ALSO do a test called A1C. This takes an 90-day average of your blood sugars. This is a good way to tell "how you're doing". You ARE diabetic, and you need the A1C test every 90 days. But it sounds like you are actually succeeding in getting the disease under control! Continue to follow doctors orders, take your medicine as prescribed, watch your diet, get more exercise, and lose weight. Maybe it will turn out that the doctor can eliminate the metformin in the near future. you're STILL diabetic, but you're doing a good job of controlling it, through diet and exercise alone. The good news is that if you continue to control the diabetes, you can expect to live as long and as happy as a normal person! EDIT: "Insulin resistance" IS a form of diabetes. Diabetes is defined as having consistently high blood sugars. It can be caused by a failing pancreas, OR by the body's inability to use insulin. Either way, it is STILL diabetes, with ALL the potential drawbacks thereof."

aceofspd replied: "Type 2 diabetes is a disease of too much insulin released because your body does not respond to a normal amount of insulin known as insulin resistance. When your body can no longer produce enough insulin to over come the resistance, your blood sugar goes up. So to recap, you have high sugar levels due to chronic high insulin levels, so your doctor gives you a drug that causes you to release more insulin. You are treating a symptom while perpetuating the disease. Can you say "Quack" ? Just because your doctor declares that you are a diabetic, does not mean that you have will be a diabetic the rest of your life. You might have to watch your carb intake the rest of your life, but only as a preventive measure. At this early stage in the disease, you can defiantly cure yourself. Your cells became resistant do to over exposure to insulin. You caused insulin release by consuming carbohydrates, even "complex". Sever restriction of carbohydrates, even for a short time, will re sensitize your cells to insulin. At the same time you give your pancreas a chance to rest from the over production of insulin that was required to overcome the resistance. At the same time you will lose some weight, and everyone agrees to that benefit. Food for thought, does being overweight cause diabetes, or does diabetes cause you to be overweight?"

Rhia replied: "You could be developing a resistance to insulin and your doctor wants to prevent that. Are you overweight? I'd suggest seeing a dietitian to help you get and keep on track with weight management so that you won't become insulin dependent. As for the Metformin, it acts by increasing the sensitivity of liver, muscle, fat, and other tissues to the uptake and effects of insulin. These actions lower the level of sugar in the blood. Follow up with your doctor AND a nutritionist or dietitian for more information."

Is Metformin HCL part of the Cloriquin family as I have psoriasis and seemed to get the same allergic reaction caused super flare up of scale intense itching, rash and sharp pain in hands.

brisk131 replied: "Metformin is in no way related to Chloroquine. And none of the symptoms are common side affects of the medication. It could be caused by drug interactions, or some new factor introduced into your life."

Does taking Metformin HCL have an affect on Depression? I have been suffering with depression / low self esteem for a few years now. Recently I found my dad also has depression and has a pre ion for it. Today I took one of the pills I thought were his depression pills but turned out to be Metformin HCL which is used to treat high blood sugar and those with diabetes, which my father also has. After I took the pill I felt amazing and not depressed the entire day without yet knowing the pill wasn't for depression. Was it the placebo affect that made me so happy from taking one of these diabetes pills or is it actually used as a drug for this purpose?

Orion replied: "I did a little research on this subject and was unable to find a connection between depression and Metformin and HCL. However considering your father takes this for diabetes it is possible that you to carry the genetic traits that can result in diabetes. Whatever the reason is whenever your body chemistry is off which includes insulin production it can make you feel very tired and depressed. It is also possible that you had an expectation that you would feel better therefore you did. It's amazing what you can do for your own body when you stop stressing over all that goes on in life. My suggestion would get a complete physical and talk with your physician about how insilin productions can affect how you feel."

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